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產(chǎn)品編號 |
英文名稱 |
CAS號 |
包裝 |
|
Y3710 |
Curcumin |
458-37-7 |
可根據(jù)客戶要求訂制 |
產(chǎn)品編號：Y3710
英文名稱：Curcumin
CAS號：458-37-7分析標(biāo)準(zhǔn)品
分子式 C21H20O6 分子量368.38
基本信息:
屬性
密度 0.93
熔點(diǎn) 183°C
描述
產(chǎn)品介紹 易溶于冰乙酸，能溶于醇，不溶于醚帶淡綠色熒先，溶于堿呈紅棕色，加酸于堿液后變?yōu)榈S色并析出姜黃素沉淀，溶于濃硫酸帶黃紅色，不溶于水。
別名 克扣明;姜黃色素;川芎內(nèi)酯 B;1,7-雙(4-羥基-3-甲氧基苯基)-1,6-庚二烯-3,5-二酮;(E,E)-1,7-雙(4-羥基-3-甲氧基苯基)-1,6-庚二烯-3,5-二酮;Natural Yellow 3;Diferuloylmethane;Diferulylmethane;(E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
生化機(jī)理
Description:
IC50 Value: N/A
Curcumin is a natural phenolic compound with impressive antioxidant properties. Curcumin is recently proved to exert its chemopreventive effects partly through the activation of nuclear factor (erythroid-2 related) factor 2 (Nrf2) [1]. Curcumin possesses chemopreventive properties against several types of cancer, but the molecular mechanisms by which it induces apoptosis of cancer cells and inhibits cancer cell proliferation are not clearly understood.
in vitro: curcumin induced the expression of forkhead box protein O1 (FOXO1) through activation of extracellular signal-regulated kinase 1/2 signaling. Curcumin inhibited cell proliferation, which was associated with upregulation of the cyclin-dependent kinase inhibitors, p27 and p21, and downregulation of cyclin D1 [2]. Treatment of AGS and HT-29 cells with curcumin enhanced the cleavage of procaspase-3, -7, -8 and -9. Meanwhile, curcumin induced endoplasmic reticulum (ER) str
應(yīng)用 酸堿指示劑，pH7.8(黃)～9.2(紅棕)。顯色反應(yīng)測鈹、鋯和鎂，硼酸鹽和試劑。
密度 0.93
熔點(diǎn) 183°C
描述
產(chǎn)品介紹 易溶于冰乙酸，能溶于醇，不溶于醚帶淡綠色熒先，溶于堿呈紅棕色，加酸于堿液后變?yōu)榈S色并析出姜黃素沉淀，溶于濃硫酸帶黃紅色，不溶于水。
別名 克扣明;姜黃色素;川芎內(nèi)酯 B;1,7-雙(4-羥基-3-甲氧基苯基)-1,6-庚二烯-3,5-二酮;(E,E)-1,7-雙(4-羥基-3-甲氧基苯基)-1,6-庚二烯-3,5-二酮;Natural Yellow 3;Diferuloylmethane;Diferulylmethane;(E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
生化機(jī)理
Description:
IC50 Value: N/A
Curcumin is a natural phenolic compound with impressive antioxidant properties. Curcumin is recently proved to exert its chemopreventive effects partly through the activation of nuclear factor (erythroid-2 related) factor 2 (Nrf2) [1]. Curcumin possesses chemopreventive properties against several types of cancer, but the molecular mechanisms by which it induces apoptosis of cancer cells and inhibits cancer cell proliferation are not clearly understood.
in vitro: curcumin induced the expression of forkhead box protein O1 (FOXO1) through activation of extracellular signal-regulated kinase 1/2 signaling. Curcumin inhibited cell proliferation, which was associated with upregulation of the cyclin-dependent kinase inhibitors, p27 and p21, and downregulation of cyclin D1 [2]. Treatment of AGS and HT-29 cells with curcumin enhanced the cleavage of procaspase-3, -7, -8 and -9. Meanwhile, curcumin induced endoplasmic reticulum (ER) str
應(yīng)用 酸堿指示劑，pH7.8(黃)～9.2(紅棕)。顯色反應(yīng)測鈹、鋯和鎂，硼酸鹽和試劑。
