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錨定蛋白重復(fù)結(jié)構(gòu)域蛋白激酶ANKK1抗體

文字:[大][中][小] 2017-5-4    瀏覽次數(shù):1216    

                                 錨定蛋白重復(fù)結(jié)構(gòu)域蛋白激酶ANKK1抗體                                                                                                                                                
英文名稱(chēng)  Anti-ANKK1 
中文名稱(chēng)  錨定蛋白重復(fù)結(jié)構(gòu)域蛋白激酶ANKK1抗體 
別    名  Ankyrin repeat and kinase domain containing 1; Ankyrin repeat and protein kinase domain containing protein 1; EC 2.7.11.1; PKK2; Protein kinase PKK2; SGK288; Sugen kinase 288; X kinase; ANKK1_HUMAN. 

詳細(xì)介紹:


濃    度  1mg/1ml 
規(guī) 格  0.2ml/200μg  
抗體來(lái)源  Rabbit  
克隆類(lèi)型  polyclonal 
交叉反應(yīng)  Human, Mouse, Rat, Chicken, Dog, Horse  
產(chǎn)品類(lèi)型  一抗    
研究領(lǐng)域  信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 細(xì)胞分化  
蛋白分子量  predicted molecular weight: 85kDa 
性    狀  Lyophilized or Liquid 
免 疫 原  KLH conjugated synthetic peptide derived from human ANKK1 
亞    型  IgG 
純化方法  affinity purified by Protein A 
儲(chǔ) 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 
產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 
(石蠟切片需做抗原修復(fù)) 
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.  
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

相關(guān)資料:


產(chǎn)品介紹 The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. ANKK1 (ankyrin repeat and kinase domain containing 1), also known as PKK2 or SGK288, is a 765 amino acid protein that belongs to the Ser/Thr protein kinase family and contains 12 ANK repeats and one protein kinase domain. Highly expressed in brain tissue and present in lower amounts in placenta and spinal cord, ANKK1 functions to catalyze the ATP-dependent phosphorylation of target proteins and is thought to play a role in alcohol and nicotine dependence. The gene encoding ANKK1 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
Function : ANKK1 belongs to the TKL Ser/Thr protein kinase superfamily, contains twelve ANK repeats and one protein kinase domain. The protein is weakly expressed in testis, placenta, and spinal cord.
Tissue Specificity : Highly expressed in brain and weakly expressed in placenta and spinal cord.
Similarity : Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. 
Contains 12 ANK repeats.
Contains 1 protein kinase domain.
Database links : UniProtKB/Swiss-Prot: Q8NFD2.1

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