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骨形態發生蛋白15抗體

文字:[大][中][小] 2017-5-4    瀏覽次數:1386    

英文名稱 Anti-BMP15
中文名稱: 骨形態發生蛋白15抗體
別 名 BMP 15; BMP-15; BMP15; BMP15_HUMAN; Bone morphogenetic protein 15; GDF 9B; GDF-9B; GDF9B; Growth/differentiation factor 9B; ODG2; POF4.

詳細介紹:


濃 度 1mg/1ml
規 格 0.1ml/100μg 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep
產品類型 一抗
研究領域 心血管 發育生物學 染色質和核信號 信號轉導 干細胞 生長因子和激素 轉錄調節因子
蛋白分子量 predicted molecular weight: 14kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human BMP15
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產品應用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

相關資料:


產品介紹 The BMP15 protein is a member of the bone morphogenetic protein family which is part of the transforming growth factor beta superfamily. The transforming growth factor beta superfamily includes large families of growth and differentiation factors. It is thought that BMP15 may be involved in oocyte maturation and follicular development as a homodimer, or by forming heterodimers with a related protein, Gdf9.
Subunit : Homodimer. But, in contrast to other members of this family, cannot be disulfide-linked.
Subcellular Location : Secreted.
Similarity : Belongs to the TGF-beta family.
[DISEASE] Defects in BMP15 are the cause of ovarian dysgenesis type 2 (ODG2) ; also known as X-linked hypergonadotropic ovarian dysgenesis or hypergonadotropic ovarian failure due to ovarian dysgenesis. Ovarian dysgenesis leads to ovarian failure and accounts for about half of the cases of primary amenorrhea.

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