產(chǎn)品編號：Y3283
英文名稱：Angelicin
CAS號 523-50-2  
分析標(biāo)準(zhǔn)品
分子式 C11H6O3 分子量186.16

基本信息:

敏感性 對熱敏感
密度 1.389
溶解性 Soluble in Chloroform and Methanol
存貯條件 儲(chǔ)存溫度：2-8°C
描述 
別名 異補(bǔ)骨脂素;2H-氟[2,3-h]色滿-2-酮;氟[2,3-h]苯并吡喃-2-酮;Furo[2,3-h]benzopyran-2-one;2H-Furo[2,3-h]chromen-2-one;Isopsoralen; 2-Oxo-(2H)-furo(2,3-h)-1-benzopyran
生化機(jī)理 Angular furocoumarin with diverse photobiological effects. Upon long-wavelength UV irradiation, forms monoadduct with double-stranded DNA and reacts with unsaturated fatty acids. Inhibits DNA and RNA synthesis and cell replication in Ehrlich ascites tumor cells.
應(yīng)用 An angular furocoumarin, may be used as a photoactivatable molecule that reacts with DNA and unsaturated fatty acids to form monoadducts. Angelicin may be studied as a potential phototherapeutic and to understand its mechanisms of action and effects on RNA and DNA synthesis.